Figure 8 - full size

 

Figure 8.
Figure 8. The docking model of SPINK2 with trypsin. (A) The docked complex model, trypsinogen-SPINK2, was exhibited using Accelrys DS ViewerPro.[49] The P2-P2' residues were labeled as purple color. (B) Ser195, His57 and Asp102 (shown as green line) are catalytic triad of trypsin. The P2-P2' sites are shown as ball and stick. (C) PSTI and (D) SPINK2 interact with cow trypsin at the P2-P2' sites are represented by LIGPLOT diagrams.[43] The residues in trypsin were labeled as Z and inhibitors (PSTI or SPINK2) as I .

The above figure is reprinted by permission from John Wiley & Sons, Inc.: Proteins (2009, 77, 209-219) copyright 2009.