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Figure 8.
Figure 8. The docking model of SPINK2 with trypsin. (A) The
docked complex model, trypsinogen-SPINK2, was exhibited using
Accelrys DS ViewerPro.[49] The P2-P2' residues were labeled as
purple color. (B) Ser195, His57 and Asp102 (shown as green line)
are catalytic triad of trypsin. The P2-P2' sites are shown as
ball and stick. (C) PSTI and (D) SPINK2 interact with cow
trypsin at the P2-P2' sites are represented by LIGPLOT
diagrams.[43] The residues in trypsin were labeled as Z
and
inhibitors (PSTI or SPINK2) as I
.
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