Figure 8 - full size

 

Figure 8.
Figure 8. The reaction mechanism for PLD[PMF] on a phosphatidylcholine (PC) substrate. R, Diacylglycerol (DAG); R', choline. The reaction that takes place when the product re-enters the active site and the dead-end phosphohistidine is formed is illustrated below the horizontal line.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2004, 339, 805-820) copyright 2004.