Figure 8 - full size

 

Figure 8.
Figure 8. Comparison of the AMP and 8-Br-AMP bound to PDE4B. Schematic representation of the ligand-binding mode for each molecule including the major hydrogen bond interactions seen between each ligand and the active site.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2004, 337, 355-365) copyright 2004.