Figure 8.
Figure 8 Schematic relationships among events that affect
excision-based NRTI resistance (dNTP binding, translocation,
excision). Factors that affect any stage will affect the overall
equilibrium. X is an NRTI (red), A is ATP (orange) and dNTP
(cyan) is the cognate nucleotide triphosphate.
The above figure is reprinted
from an Open Access publication published by Macmillan Publishers Ltd:
EMBO J
(2002,
21,
6614-6624)
copyright 2002.
