|
Figure 8.
Figure 8 Intra- and intermolecular contacts of the TGEV M^pro
N-terminus. (A) MOLSCRIPT stereo representation of a TGEV M^pro
dimer. Molecule A is coloured from blue at the N-terminus, via
green (domain II), to red (C-terminus), while molecule B is
shown in grey. The catalytic Cys144 and His41 residues are
labelled in both monomers. (B) Detailed view of the interactions
made by the N-terminal segment (blue) and domains II/III of
monomer A as well as domains II/III of monomer B. Residues
critically involved in these interactions are designated by the
single-letter code and shown in ball-and-stick representation
(see text for details). The N- and C-termini of molecule A are
indicated.
|
