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Figure 7.
Fig. 7. A side view of "descending molecular see-saw"
model for the translocation of HCV RNA helicase along ssRNA. The
dimer (left) translocates along the ssRNA (right) by a rotation
of about 60° (with respect to the axis of the RNA double
helix) along an axis passing the front part of RNA binding
motif. The right figure represents a translocation of the dimer
by a half-turn of RNA with respect to the location of the dimer
on ssRNA in the left figure. For clear presentation of the
translational motion, the two figures are shown with
orientations different by 180° with respect to each step.
Figs. 1, 3, and 5 were produced using the program MOLSCRIPT,
Fig. 2 using the program O, Fig. 4 using the program GRASP, and
Figs. 6 and 7 using the program QUANTA.
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