Figure 7 - full size

 

Figure 7.
Fig. 7. Schematic of the reaction mechanism catalyzed by PTP1B. A, formation of the cysteinyl-phosphate intermediate. B, hydrolysis of the cysteinyl-phosphate intermediate.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (1998, 273, 10454-10462) copyright 1998.