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Figure 7.
Fig. 7. A diverse array of SAM domain partnerships. The
Ephrin kinase SAM domains have been crystallized in Head–Head
(involving helix 1) and Tail–Tail orientations (involving
helix 5). The Head–Tail orientation to which the AIDA-1 SAM
tandem belongs is shared with the heterotypic SAM partnerships
of human/Drosophila CNK2/HYP, Drosophila Ph/Scm, and S.
cerevisiae Ste11/Ste50, among others. PDB codes of the relevant
structures are indicated.
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