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Figure 7.
Figure 7. Ribbon representation of the BCIR PSAT structure at
pH 8.5 (A) dimer (B) monomer. Secondary-structure elements were
calculated using DSSP.[29] The  -helices
are shown in yellow and the  -strands
in cyan. N- and C-termini are shown as spheres and PLP molecules
in space filling (A) and ball-and-stick (B). The small domain
contains an extended five-stranded -sheet,
composed of a two-stranded parallel -sheet
( 1
and 13)
and a three-stranded antiparallel -sheet
(+ 11,
- 12,
- 14).
The large domain contains the conservative among PLP-dependent
enzymes[44] seven-stranded -sheet
( 2-
5
and 7-
9)
with all -strands
parallel except 9.
Two additional -strands
( 6
and 10),
six -helices
( 1-
6),
and six 3[10]-helices complete the large domain. Helix 7
connects the large domain with the small domain. The
five-stranded -sheet
is flanked by helix 7
and two additional helices ( 8
and 9)
close to the C-terminus.
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