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Figure 7.
Figure 7. Model of the FAK peptide bound to the CAS SH3
domain. (a) Peptide residues are shown in green and numbered
from 1 to 9. Residues that are involved in ligand binding are
shown in ball and stick representation (the highly conserved
amino acid residues are in cyan). (b) The CA traces of the
superposed CAS SH3-FAK peptide complex (magenta) and C-Src
SH3-App12 complex (cyan) (1QWE).31 (c) Interface of the CAS
SH3-peptide complex interactions. SH3 domain is shown as a
surface plot (residues in red, negatively charged; blue,
positively charged; white, neutral), FAK peptide is shown in
green.
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