Figure 7 - full size

 

Figure 7.
Figure 7. Sp filfing model of' the NAI) vavit)~. (a) 7'hv tjop t~errodiagram represents n o~~arall \-iew of tlw KA41) (*:ivity with citrate in thi active site in a bac~kbone model of' the protein. All filled-in aeas belong to the (:a~i&y. (1)) The middle diagram represents a dose-up view of the X'AD binding wvity wit,h citrate in the active sit)e. All side-c:hnins ~II wntwt with the cavit,y are shown. (c) The bot,tom iagram represents the same feabres shown in (1)): ho\rrver. t'hr c*itrste has been c~hanged to rrpresent a malatr molrculc.

The above figure is reprinted by permission from Elsevier: J Mol Biol (1992, 226, 867-882) copyright 1992.