Figure 7 - full size

 

Figure 7.
Figure 7. Binding of 8-Br-AMP in the PDE4B active site. The protein backbone is shown as a gray ribbon. The Br is colored dark red. The carbon atoms of 8-Br-AMP are colored yellow, the phosphate is colored pink. The carbon atoms of important side-chain of the protein are shown in green. The metal ions are shown as yellow balls. The hydrogen bonds between protein and 8-Br-AMP are shown as white dotted lines. The protein interactions with metal ions are shown as cyan dotted lines.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2004, 337, 355-365) copyright 2004.