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Figure 7.
Figure 7. A stereo view of the 170 loop and the
intermediate helix. Orange, arrow pointing to the intermediate
helix (Met164-Ser170B) and Ser170H-Cys182; pink, insertion loop
(Arg170C-Asp170G); green, Trp215-Arg230; purple, sulphate; light
blue, disulfide bond Cys168-Cys182; white ball, water. Residues
Met164, Cys168, Gln170A-Asn175, Cys182, Trp215 and Arg230 are
shown including their side-chains, for the other residues, only
the backbone atoms are shown. The factor VIIa specific insertion
loop Arg170C-Asp170G and the sulphate groups are shown with
their 2F[o] -F[c] electron density maps. The hydrogen bonds
stabilising the sulphate groups are indicated by white dotted
lines.
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