Figure 7 - full size

 

Figure 7.
Figure 7. The 2F[o] -F[c] electron density map, contoured at 1.2s, around the Hg2+-binding region of the Hg-HPK structure, at 2.3 Å resolution. In the Zn-HPK structure, a zinc atom is found in the same position, coordinated by the same ligands (Asp91, His 101, His234) (see bond distances in Table 2). A probable fourth ligand is a water molecule, which is not included in the picture. His101 precedes Asp102, which, together with His57 and Ser195, form the catalytic triad. Asp91 belongs to the kallikrein loop. The picture was drawn with BOBSCRIPT [52.] and Raster3D. [51.]

The above figure is reprinted by permission from Elsevier: J Mol Biol (2002, 322, 325-337) copyright 2002.