Figure 7 - full size

 

Figure 7.
Figure 7. Stereo drawing comparing the region around Trp169[R2] in Site 2. The wt complex residues are colored in green (top). The hGH[v] complex residues are shown in yellow (bottom). Hormone residues are labeled in black and receptor residues in red. Arrows point to the carbonyl oxygen atom of the peptide bond (169) that flips the conformation of the Trp169[R2] side-chain.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2002, 316, 277-289) copyright 2002.