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Figure 8.
Figure 8. Protein–inhibitor interactions in the CDK2–HD
complex. (a) Stereo diagram showing the refined structure of HD
in the ATP-binding pocket of CDK2. Inferred hydrogen bonds are
shown as thin dotted lines. Oxygen atoms are shown in red,
nitrogen atoms in blue and bromine in green. (b) Schematic
illustration of the interactions between CDK2 and HD. Protein
sidechain contacts are indicated by lines connecting to the
respective residue box, whereas interactions with mainchain
atoms are shown as lines to the specific mainchain atom. Van der
Waals contacts are indicated by dotted lines and hydrogen bonds
by broken lines.
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