Figure 6 - full size

 

Figure 6.
Figure 6. a,Contact regions between subdomains of a protomer, in red and orange, and between neighboring protomers, in yellow and purple. b, The N-terminal and C-terminal subdomains contact through a hydrophobic patch consisting of Ile 508 and Trp 510 from the former (red), and Ile 670, Leu 682, and Leu 683 from the latter (orange). c, Between N-terminal subdomains on neighboring protomers, another hydrophobic contact is formed between Ile 574, Val 612, and Ile 614 from one protomer (purple) and the - through -carbons of Lys 586, Leu 609, Phe 618 and Val 628 from the other (yellow).

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nat Struct Biol (1998, 5, 803-811) copyright 1998.