|
Figure 6.
Figure 6. The Kapα50 Dimer in the Crystals(A) Dimer of
Kapα50 viewed approximately down the local molecular dyad axis,
with the two monomers colored in green and magenta. The arm
repeats are numbered sequentially from the N to the C terminus.
The helices of the tenth arm motifs are labeled. Note that the
first arm repeat lacks the H1 helix.(B) The dimer interactions
between the tenth arm repeat of one monomer (in gray with
relevant residues depicted in magenta) contacting the H3 helices
of the central repeats of the second monomer (in gray with
important residues highlighted in green). All the labeled side
chains are highly conserved. Hydrogen bonding contacts are shown
in dotted lines.
|