Figure 6.
Figure 6 Interactions of nucleophile, base and phosphate group.
Interactions which might occur in a general base-catalysed
reaction mechanism via: (A) the observed structure of the
ternary complex and (B) an alternative conformation modelled by
giving the attacking serine residue a 1
angle of -60°.
The above figure is reprinted
from an Open Access publication published by Macmillan Publishers Ltd:
EMBO J
(1997,
16,
6646-6658)
copyright 1997.
1
angle of -60°.