Figure 6 - full size

 

Figure 6.
Fig. 6. Choosing the correct homoharringtonine enantiomer. A stereo pair that compares the fit of the refined homoharringtonine structure (gold) to the electron density for that drug with the fit obtained for the homoharringtonine structure obtained from the CSD (green), which is its enantiomer, is provided. The electron density shown is F[o] − F[o] difference electron density contoured at 3σ.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2009, 389, 146-156) copyright 2009.