Figure 6.
Fig. 6. Comparison of the active-site regions of JAK1 and
JAK2. Superposition of JAK1 PTK (green) and JAK2 PTK (cyan) in
complex with CMP6 (a) and CP-690,550 (b). Unique residues within
5 Å of the inhibitor are shown.
The above figure is reprinted
by permission from Elsevier:
J Mol Biol
(2009,
387,
219-232)
copyright 2009.
