Figure 6 - full size

 

Figure 6.
Proposed reaction mechanism for Ga5DH from S. suis. Note that Ser150 forms a hydrogen bond with the ---OH group at C6 (not C5) of the substrate. The mechanism is described in detail in Discussion.

The above figure is reprinted from an Open Access publication published by the Protein Society: Protein Sci (2009, 18, 294-303) copyright 2009.