Figure 6.
Fig. 6. A model of the ING1 functioning. Binding of the
C-terminal PHD finger and the N-terminal SAID domain of ING1 to
H3K4me3 and a SAP30 subunit of the Sin3a/HDAC1/2, respectively,
tethers the histone modifying complex to the nucleosome for
subsequent deacetylation of acetylated lysine residues of
histone H3.
The above figure is reprinted
by permission from Elsevier:
J Mol Biol
(2008,
380,
303-312)
copyright 2008.
