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Figure 6.
Figure 6. Mechanism of Gate Opening in the 20S Induced by PAN
and PA26 Complexes
(A) (Left) Overlay of the α ring
structures, before and after the binding of the gate-opening
peptides. (Right) Enlarged view of the dashed area from the
left. Pro17 is shifted because of the rotation in α subunit.
(B) (Left) Overlay of the structure of the α ring, before
and after PA26 binding. (Right) Enlarged view of the dashed
area. Pro17 is shifted by the activation loop of PA26 (data not
shown). Notice that Pro17 in red and magenta structures is in a
similar position.
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