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Figure 6.
Simplified folding model of tANK. The protein folds via an
on-pathway intermediate in which the two N-terminal repeats are
unfolded and the three C-terminal repeats are natively folded.
Additional NMR cross-peaks of the intermediate state, which do
not show a random coil chemical shift, and CD data suggest that
there is some residual secondary structure in AR 1 and 2.
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