Figure 6 - full size

 

Figure 6.
Figure 6. Overlay of lck/imatinib complex (green) with src (C-helix-out conformation) (gray) (PDB ID: 2SRC).[13] Side chains of key residues are shown as sticks. Hydrogen bond between lck residues W238/E237 and src residues W260/Q312 are shown as dotted line. Also shown are side chains of src A259 and lck N290. These residues are at the same position as lck residue E237 and src residue Q312, respectively.

The above figure is reprinted by permission from John Wiley & Sons, Inc.: Proteins (2008, 70, 1451-1460) copyright 2008.