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Figure 6.
Figure 6. DNA Substrate Recognition by TelK
(A) A
schematic diagram showing the DNA backbone and base-specific
interactions. The protein residues are color coded for each
domain according to the scheme in Figure 4C, and DNA backbones
are colored to match the structural figures. DNA bases involved
in hydrogen-bonding interactions are colored yellow, and those
involved in van der Waals contacts are colored cyan. Solid and
dashed lines denote electrostatic/hydrogen-bonding and van der
Waals interactions, respectively.
(B and C) Base-specific
hydrogen-bonding interactions made by the core-binding and
catalytic domains (B) and by the C-terminal stirrup domain (C).
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