Figure 6.
FIGURE 6. Stereo view of mutator residues. Amino acids of
that
lead to a mutator phenotype when specifically substituted are
shown in red on the structure of the 186-HOT complex. HOT is
in orange, and 186 is in blue. Known
mutator residues are Asp^12 (a), Glu^14 (b), Thr^15 (c), Thr^16
(d), Gly^17 (e), Arg^56 (f), His^66 (g), Val^96 (h), Asp^103
(i), His^162 (j), Ala^161 (k), Asp^167 (m), Leu^171 (n), and
Gly^180 (o).
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2006,
281,
38466-38471)
copyright 2006.
that
lead to a mutator phenotype when specifically substituted are
shown in red on the structure of the