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Figure 6.
Figure 6. Structural similarities between B-box1, RING,
U-box and ZZ domains. (a) Ribbon representation of RING domains
from the breast cancer susceptibility protein, BRCA1 (1JM7),
CDK-activating kinase assembly factor, MAT1 (1G25), a schematic
representation of a canonical RING structure, the U-box domain
from E4A, the ZZ domain from CBP/p300, and the B-box1 domain
from MID1. (b) Consensus zinc-binding motifs of RING, ZZ, U-box
and B-box1 domains; X=any amino acid, C and H are cysteine and
histidine, zinc-binding residues.
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