Figure 6.
FIGURE 6. Model of CG-05 bound to plasma kallikrein,
showing expected interaction of the diacid group of the
inhibitor with Lys192 of the enzyme, along with the
multicentered short hydrogen bond array observed at the active
site of the trypsin complex. Short hydrogen bonds are shown in
cyan.
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2005,
280,
41077-41089)
copyright 2005.
