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Figure 6.
Figure 6. Road Maps of the ICAM-1^Kilifi Contact Area with
CVA21
(A) Stereo diagram of enlarged contact area in Figure
5A.
(B) The viral (left) and ICAM-1^Kilifi (right) residues
that are in the virus/receptor interface are shown on a
two-dimensional projection of the same contact area (orange) as
in (A). The three contour lines represent virus-receptor
separation distances of 2.0 (red), 3.0 (orange), and 4.0
(yellow) Å.
(C) Stereo diagram of the contact area (white)
with surface color based on electrostatic potentials. Positively
and negatively charged surfaces are colored blue and red,
respectively.
(D) Two-dimensional projection of (C) with a
roadmap of corresponding residues of CVA21 (left) and
ICAM-1^Kilifi (right). The four ionic network sites are
encircled with green dashed lines and are labeled with
green-colored letters of a, b, c, and d, corresponding to the
notation used in Figure 7.
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