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Figure 6.
Figure 6. A Model for the DnaB-P16 Interaction
(A) The
3-fold symmetric ring of hexameric DnaB, showing the N-domain of
one monomer (6N) interacting with the C-domain (5H) of the
neighboring monomer (Yang et al., 2003).
(B) In the
DnaB-P16 complex, the P16 protein (shaded purple) interacts with
the linker region that connects the N-terminal (6N) and
C-terminal (6H) domains of one monomer, via its C2 subdomain. In
addition, the C1 subdomain displaces 6N while at the same time
maintaining the interactions with 5H that are essential to
preserve a 3-fold symmetric ring in the helicase-primase complex.
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