|
Figure 6.
Fig. 6. Quaternary complex of CDK (green), cyclin (red),
and PCNA (blue). The model was produced by fitting together the
"RRLIF sequences" from the two crystal complexes [PCNA/p21
(Protein Data Bank ID code 1AXC [PDB]
) with the labeled peptide in yellow] and CDK/cyclin/RRLIF
(Protein Data Bank ID code 1OKV [PDB]
) with the peptide colored cyan. The exploded view shows that
the RRLIF conformations in the cyclin A- and PCNA-bound
structures are very similar.
|