Figure 6 - full size

 

Figure 6.
Fig. 6. Quaternary complex of CDK (green), cyclin (red), and PCNA (blue). The model was produced by fitting together the "RRLIF sequences" from the two crystal complexes [PCNA/p21 (Protein Data Bank ID code 1AXC [PDB] ) with the labeled peptide in yellow] and CDK/cyclin/RRLIF (Protein Data Bank ID code 1OKV [PDB] ) with the peptide colored cyan. The exploded view shows that the RRLIF conformations in the cyclin A- and PCNA-bound structures are very similar.