Figure 6 - full size

 

Figure 6.
Figure 6. Comparison of Alternate DNA and N-Subdomain ConformationsThe conformation of the N subdomain, as monitored by the position of a helix N, for the NAC mismatch structure (green) is in an intermediate position relative to the active closed (blue; Protein Data Bank entry 1BPY) or inactive open (red; Protein Data Bank entry 1BPX) conformations. These structures were superimposed using the C subdomains. The template strand is displaced to a greater extent than that observed for the open binary DNA complex relative to the closed ternary complex. The position of a helix N and the template strand in the open nicked complex (not shown; Protein Data Bank entry 1BPZ) is identical to that illustrated for the open complex.

The above figure is reprinted by permission from Cell Press: Structure (2004, 12, 1823-1832) copyright 2004.