Figure 6 - full size

 

Figure 6.
Fig. 6. Structural variation in residues 81–82 near indinavir. Stereoview showing the benzyl group of indinavir interacting with residues 81–82, using the major conformation of Val82. The wild-type HIV-1 protease (PR) structure is in black and the mutant is in gray bonds. Interatomic distances are given in Å. (A) PR[V82A] superimposed on PR. (B) PR[L90M] superimposed on PR.

The above figure is reprinted by permission from the Federation of European Biochemical Societies: Eur J Biochem (2004, 271, 1516-1524) copyright 2004.