Figure 6 - full size

 

Figure 6.
FIG. 6. A comparison of the yeast and human ESCRT-I UEVs. Left, representations of the Vps23 UEV/Ub complex; right, representations of the Tsg101 UEV complex with a PTAP-peptide from the HIV-1 p6 protein (65). The vestigial active-site loop is colored cyan and the -hairpin tongue and lip are colored red. The Ub bound to the Vps23 UEV is colored green, and the PTAP peptide bound to Tsg101 is colored black.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2004, 279, 28689-28696) copyright 2004.