Figure 6 - full size

 

Figure 6.
Figure 6 Stereoview of (a) the superposition of the complexes PPE-HEI-TOE I (green/red) and HLE-OMTKY3 (blue/yellow), schematic representation, (b) the hybrid inhibitor HEI-TOE I (red) bound to PPE (green; active-site Ser195 in dark green), important side-chain contacts for the binding-loop sequence PCTLEYMR, (c) the OMTKY3 inhibitor (yellow) bound to human leukocyte elastase (blue; active site Ser195 dark blue), important side-chain contacts for the binding-loop sequence ACTLEYRP.

The above figure is reprinted by permission from the IUCr: Acta Crystallogr D Biol Crystallogr (2003, 59, 247-254) copyright 2003.