Figure 6 - full size

 

Figure 6.
Figure 6. The binding of a-tocopherol in molecule A. The OH group of the aromatic moiety in a-tocopherol plays a key role by interacting simultaneously with both Asp49 and His48. The hydrocarbon chain of a-tocopherol fills the hydrophobic channel in the protein. The Figure was drawn with MOLSCRIPT23 and rendered by Raster3D.22

The above figure is reprinted by permission from Elsevier: J Mol Biol (2002, 320, 215-222) copyright 2002.