Figure 6 - full size

 

Figure 6.
Fig. 6. Grasp rendering of the PTP1B and TC-PTP surfaces. The two surface areas with structural differences useful for potential selectivity design are indicated by white and yellow circles, respectively. The surface electrostatic potentials are colored in blue for positive charges and in red for negative charges.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2002, 277, 19982-19990) copyright 2002.