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Figure 6.
Figure 6. View Into Putative PNPase Active Site(a)
Difference density at tungstate binding site with contours at 5
s (colored green). Overlaid is 2F[O]-F[C] sigmaa-weighted map
[45] and final refined model for tungstate derivative with
contours at 1.00 s (the model is colored red on outer and purple
on inner surfaces).(b) Secondary structure and key conserved
residues around the tungstate binding site. Sidechain atoms of
residues in tungstate binding loop and other key conserved
residues are shown. Residues of two additional conserved loops
are shown as colored Ca positions and numbered in corresponding
color. Residues 458-460 are shown with serine, asparagine, and
glycine colored pink, green, and black, respectively; residues
369-371 are shown with arginine, glycine, glutamic acid, and
threonine colored blue, black, orange, and pink, respectively;
and residues 412-413 are shown with glycine and glutamic acid as
black and orange, respectively
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