Figure 6 - full size

 

Figure 6.
Figure 6. Comparison of Ins(1,3,4,5)P[4] Recognition by the Grp1 and Btk PH Domains(A) Space-filling representation with invariant residues of the signature motif shown in white and nonconserved residues from the three SDRs highlighted in green (β1/β2 loop), magenta (β3/β4 loop), and orange (hairpin insertion).(B) Schematic diagram showing direct interactions with the head group. Residues in the signature motif are indicated in blue.

The above figure is reprinted by permission from Cell Press: Mol Cell (2000, 6, 385-394) copyright 2000.