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Figure 6.
Figure 6 Superposition of the bovine trypsin (V) and human
factor Xa DX-9065a (PDB entry 1fax) complexes. The C atoms of
the inhibitor (V) and DX-9065a are colored green and blue,
respectively. The majority of the C atoms in trypsin are colored
gray and in factor Xa are colored black. C atoms of the five
amino-acid changes between bovine trypsin and human factor Xa
(Asn/Asp97, Tyr/Leu99, Gln175/Phe174, Ser/Ala190 and Ser/Glu217)
have been colored green in trypsin and purple in human factor
Xa. The catalytic triad residues (Ser195, His57 and Asp102) in
both structures are colored orange.
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