Figure 5 - full size

 

Figure 5.
Figure 5 The interface between NFAT and AP-1. a, Surface representation (made with GRASP) showing the partly discontinuous character of the contacts. The box indicates the region shown in detail in b. The orientation is essentially the same as in Fig. 3c. b, Detailed view (using Ribbons50) of the contacts between the E'F and CX loops of NFAT (right) and Jun and Fos (left), respectively. Note the very extensive network of hydrogen bonds and salt bridges.

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nature (1998, 392, 42-48) copyright 1998.