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Figure 5.
Fig. 5. Partial characterization of IgE epitope areas.
The molecular surface of Der f 2 was produced by the program
GRASP (45) and colored according to the results from the
site-directed mutagenesis experiments (42). Red, residues whose
substitution decreased^ IgE binding; blue, residues whose
substitution did not decrease^ IgE binding; white, residues that
were not tested. The top figure^ can be related to Fig. 2 by
105° x rotation, and the bottom can be related to the top by
180° x rotation.
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