Figure 5 - full size

 

Figure 5.
Figure 5 a, Topology of -chain (green) and -chain (red) C-terminal domains. The first residue in each segment of secondary structure is numbered. b, Stereo depiction of superposed C backbone structures from globular portions of -chains (green) and -chains (red); the numbers on the strands and letters on the helices correspond to the secondary structure designations in Fig. 4. c, GRASP representation of binding cavities of -chains (left) and -chains (right) showing charge distribution; red, negatively charged; blue, positively charged^47. Domains have been reorientated to show equivalent projections.

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nature (1997, 389, 455-462) copyright 1997.