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Figure 6.
Figure 6. The environment of the phosphotyrosine side-chain in the pYEEI complex. The phosphate group is involved
in an intricate network of hydrogen-bonding and charge--charge interactions (thin green lines) with residues in the SH2
domain (thin black lines) and water molecules (red dots). The three terminal oxygen atoms are numbered. The aromatic
ring of the phosphotyrosine is situated between the aliphatic portion of Lys182 (bD6) and the guanidinium group of
Arg134 (aA2).
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