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Figure 5.
Fig. 5. The kindlin-1 F0 domain is required for targeting to
FAs. Images of CHO cells stably expressing αIIbβ3 integrin
transiently transfected with GFP-tagged kindlin-1 wild-type, F0,
and ΔF0 expression constructs after 4 h growth on
fibrinogen-coated coverslips. GFP-kindlin-1 co-localizes with
endogenous vinculin at FAs (white arrows). Neither GFP-kindlin-1
F0 nor GFP-kindlin-1ΔF0 clusters in vinculin-rich FAs.
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