Figure 5.
An overlay of the coordinates of the Chk2-NSC 109555 (PDB
code: 2W0J), Chk2-ADP (PDB code: 2CN5), and Chk2-DBQ (PDB code:
2CN8) crystal structures comparing the orientations of NSC
109555 (blue stick), ADP (orange stick), and DBQ (purple stick)
in the ATP-binding pocket of Chk2 (green stick). The coordinates
for the amino acid side chains are for the refined model of Chk2
in complex with NSC 109555.
The above figure is reprinted
from an Open Access publication published by the Protein Society:
Protein Sci
(2009,
18,
92-100)
copyright 2009.
