Figure 5.
Figure 5: Recognition of the DELLA domain by GID1A. a, A top
view of the GID1A core domain (light blue) and the N-terminal
extension (cyan) with the GAI DELLA domain (pink). The view
corresponds to Fig. 2b, d. b, A close-up view of the thumb helix
A
hooked onto the GID1A crevice. Residues of the DELLA motif
(residues D28–V38) are highlighted in green. Hydrogen bonds
are indicated with dotted lines. A bridging water molecule
inside the loop is shown as a red sphere. c, The LExLE motif
(M43–M57). d, The VHYNP motif (T72–M87). In b–d, the
residues in each motif that directly contact GID1A are
highlighted in green.
The above figure is reprinted
by permission from Macmillan Publishers Ltd:
Nature
(2008,
456,
459-463)
copyright 2008.
A
hooked onto the GID1A crevice. Residues of the DELLA motif
(residues D28–V38) are highlighted in green. Hydrogen bonds
are indicated with dotted lines. A bridging water molecule
inside the loop is shown as a red sphere. c, The LExLE motif
(M43–M57). d, The VHYNP motif (T72–M87). In b–d, the
residues in each motif that directly contact GID1A are
highlighted in green.