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Figure 5.
Figure 5. Insights to CTD Recognition
(A) Surface
representations for SpFcp1 with domains colored as in Figure 1.
A red asterisk indicates the active site Asp170-BeF[3]-Mg.
Proposed CTD path through the Fcp1 canyon is indicated by a
dashed line.
(B) Surface representation for the Scp1-CTD
complex (Zhang et al., 2006; PDB 2GHT) aligned to SpFcp1 in (A).
The S[5P]-CTD ligand is depicted as a stick model with its N and
C termini labeled. The dashed arrow indicates the CTD path on
the Scp1 surface.
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